Comparison of two different in vivo SPF values


The Challenge

During development of a sunscreen product or for a quick verification of the efficacy of a new product or batch, an in vivo screening of the SPF is often used with a small number of volunteers and we do not have an objective tool to take a decision in terms of equivalence on UVB protection.

The Solution

From the results of in vivo SPF obtained on a reference product and a product to be compared, a statistical approach [1] helps you to determine if the two products have an equivalence at the UVB protection level. Of course, equivalent UVA protection and compliance with the regulations in force are also necessary.

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[1] M. Pissavini, O. Doucet and O. Brack, Interpretation of SPF in vivo Results: Analysis and Statistical Explanation, Cosm & Toil 126(3) 172-184 (March 2011).
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